A Case of Duodenal Carcinoma of Brunner's Gland Origin

Masanobu Komatsur¹⁾²⁾, Hiroyuki Kato¹⁾, Toshiharu Motohara¹⁾, Mitsuhiro Kaji¹⁾, Tsuyoshi Miyake¹⁾, Naoki Miyazaki¹⁾, Katsunori Saito¹⁾²⁾, Masaru Kawamura³⁾

¹⁾Second Department of Surgery, Hokkaido University School of Medicine
²⁾Department of Surgery, Iwanai Kyokai Hospital
³⁾Department of Surgery, Yoichi Kyokai Hospital

This study presents a case of carcinoma of Brunner's gland origin in a 7l-year-old man. Roentgenography and endoscopy revealed a submucosal tumor with an ulcerated surface, in the second part of the duodenum. Biopsy disclosed a moderately differentiated adenocarcinoma, and pancreatoduodenectomy was performed. The lesion presented as a dome-shaped submucosal tumor 2.7×3.3 cm in size with a deep excavation on its surface. The tumor had no connection to Vater's papilla, the common bile duct, or the pancreatic duct. Following macroscopical, histological, and electron microscopical examinations, this case was diagnosed as carcinoma of Brunner's gland origin. Duodenal carcinoma originating from Brunner's gland was extremely rare, but recently some cases have been reported. We collected 21 similar cases reported in Japan to review the macroscopical and histological features.

Key words
carcinoma of the Brunner's gland, submucosal tumor of the duodenum, image diagnosis

Reprint requests
Masanobu Komatsu Iwanai Kyokai Hospital
170, Sakae, Iwanai, Hokkaido, 045 JAPAN

Accepted
February 9, 1994

To read the PDF file you will need Abobe Reader installed on your computer.