Invaginating Neurofibroma of the Colon

Kazuhito Adachi, Shum Kudo, Hiroyuki Mori, Yoshimi Horiuchi, Jinichi Kameyama*, Masaru Tsukamoto*

Department of Surgery, Sanyudo Hospital
*First Department of Surgery, Yamagata University School of Medicine

We report an extremely rare case of invaginating neurofibroma of the colon that was not associated with von Recklinghausen's disease. The patient was an 80-year-old woman whose complaints were melena and intermittent abdominal pain. Barium enema study, endoscopic examination and CT scan showed that an intraluminal tumor of the ascending colon measuring over 5 cm invaginated the transverse colon, and indicated that the tumor was non-epithelial. Right hemi-colectomy was done. The postoperative histological findings showed that the tumor was a neurofibroma. Neurofibroma must be differentiated from other non-epithelial tumors. This histological classification can be achieved by hematoxillin-eosin staining and immunohistochemical study with anti-myoglobin antibody, anti-S-100 antibody and so on. This patient is the fifth such case reported in Japan.

Key words
neurofibroma of the colon, anti-S-100 antibody, invagination

Reprint requests
Kazuhito Adachi Department of Surgery, Sanyudo Hospital
6-1-219 Chuo, Yonezawa-shi, 992 JAPAN

Accepted
May 11, 1994

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