Clinicopathological Studies of Colorectal Carcinoma with Macroscopic Invasion to Adjacent Organs -Special Reference to its Histologic Classification and Significance of Combined Resection of Colorectal Cancer and Surrounding Organs-

Hiroo Oshita, Sengai Tanaka, Hiromi Tanemura

Department of Surgery, Gifu City Hospital

Of 458 patients with colorectal cancer operated on during a lO-year period, 89 (19.4%) had macroscopic invasion to the adjacent organs. Only 36 (40.4%) of them were verified microscopically to have tumor invasion to the adjacent organs, and in cases of well differentiated adenocarcinoma, the rate of the cases with submucosal, proper muscular and subserosal invasion was as high as 29.8%. The rate of lymph node metastasis was as relatively low as 44.3%, and it was shown that patients with lower grade differentiation in histologic type had a higher frequency of distant lymph node metastasis. Eighty two of the 89 patients (92.1%) underwent combined resection of the colorectal tumor and the adjacent organs, resulting in curative resection in 53 patients (59.6%). The five-year survival rate was as relatively high as 63.9% in colorectal cancers with macroscopic invasion, and no significant difference in prognosis was found among the all histologic types. Therefore, combined resection of the cancer and the surrounding organs is recommended for better prognosis in colorectqal cancers, if they are suspected to have direct invasion.

Key words
colorectal carcinoma with invasion to the adjacent organs, combined resection of the adjacent organs in colorectal carcinoma

Reprint requests
Hiroo Oshita Department of Surgery, Gifu City Hospital
7-1 Kashimacho, Gifu, 500 JAPAN

Accepted
January 11, 1995

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