A Case of Gastric Liomyosarcoma with Cartilage Formation

Hirohiko Satoh, Masaharu Nishi, Hiroo Takehara, Nobuhiko Komi

First Department of Surgery, School of Medicine, The University of Tokushima

A case of gastric leiomyosarcoma with cartilage formation is reported. The patient was a 60-year-old man. The tumor was located on the posterior wall of the middle body of the stomach. The intracanaliculartumor size was 44×37×26 mm, and the extracanalicular size was 84×74×76 mm. The tumor weighed 420 g, and was of the mixed type in Skandalakis's classification. Histological examination of hematoxylin-eosin (HE) stained specimens revealed high cellularity of spindle cells with frequent mitosis. The part that showed leiomyosarcoma was positive for α-smooth muscle actin on immunohistochemical staining, and cartilage formation like cartilage differentiation was slightly basophilic on HE staining. The portion with cartilage formation like cartilage differentiation showed metachromasia on toluidin-blue staining, was stained blue with arushian blue stain and was positive for S-100 protain stain. Thus the diagnosis of gastric leiomyosarcoma with cartilage formation was made. As far as we investigated, a case of gastric leiomyosarcoma with cartilage formation has not been reported in Japan.

Key words
leiomyosarcoma of stomach, cartilage formation

Reprint requests
Hirohiko Satoh First Department of Surgery, School of Medicine, The University of Tokushima
3-18-15 Kuramoto-cho, Tokushima, 770 JAPAN

Accepted
January 11, 1995

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