CASE REPORT
A Case of Duodenal Argyrophil Cell Carcinoma with Pleomorphism -So Called Malignant Carcinoid-
Yoshihiro Moriwaki, Syuuhei Morita, Takuya Kudo, Ken Yamanaka, Hiroyuki Kure, Kazutaka Koganei
Department of Surgery, Yokohama Red Cross Hospital
We report a patient with duodenal argyrophil cell carcinoma, who was curatively operated on. A 69-year-old male was admitted to the Yokohama Red Cross Hospital because of abdominal pain. Although the preoperative upper gastrointestinal series and gastroendoscopic examination and biopsy indicated antral gastric cancer, laparotomy was performed and a diagnosis of duodenal cancer was made. We performed pancreatoduodenectomy with regional lymph node dissection. Histopathological examination of the resected specimen revealed ribbon-like trabecular arrangement and irregular sized atypical cells positive for both Grimelius and Fontana-Masson method. We made a diagnosis of "duodenal argyrophil cell carcinoma (so called malignant carcinoid)". Duodenal carcinoid is unrare. But most reported cases have been "classical carcinoids". That were histologically conformed of uniform, round cells and cases with pleomorphic feature were very rare. The character of this tumor is discussed compared with that of "classical carcinoid" reported as a literature in Japan.
Key words
duodenal argyrophil cell carcinoma, duodenal carcinoid, duodenal endocrine cell carcinoma
Jpn J Gastroenterol Surg 28: 845-849, 1995
Reprint requests
Yoshihiro Moriwaki Department of Surgery, Yokohama Red Cross Hospital
2-85 Negishi-cho, Naka-ku, Yokohama, 231 JAPAN
Accepted
January 11, 1995
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