Effexts of Japanese Kampo Medicine on Restoration after Sugery of the Patients with Digestive Tract Cancer

Takashi Okamoto, Motonori Sairenji, Hisahiko Motohashi, Syoji Takemiya, Yukio Sugimasa, Osamu Kobayashi, Makoto Akaike

Department of Surgery, Kanagawa Cancer Center Hospital

Changes in cellular immune response and nutritional condition following administration of chinese harbal medicines have been presumed as background factors for the improvement of QOL after surgery. In experiments in mice, it has been clarified that administration of Juzen-taiho-to contributes facorably to body weight gain. We also demonstrated that a cachectic condition in mice induced by TNF is improved by Juzen-taiho-to. Increase in body weight was observed in the group fed mixed Juzen-taiho-to after injection of TNF. The tumor strain colon-26 with cachectin-inducing action was transplanted in mice. Prolongation of survival was observed in the group administered Juzen-taiho-to compared with the contrl group. The increase in the rate of body weight gain in the group adminisstered Juzen-taiho-to was prominent. Elevation of NK activity in the group administered Jiuzen-taiho-to was also observed compared with that in the control group.

Key words
traditional chinese medicine, quality of life, post intestinal tract surgery

Reprint requests
Takashi Okamoto Department of Surgery, Kanagawa Cancery Center Hospital
54-1 Nakaomachi. Asahiku, Yokohama, 241 JAPAN

Accepted
December 7, 1994

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