A Case Report of Basaloid-(Squamous) Carcinoma of the Esophagus

Yutaka Nishida, Toichi Kushibuchi, Shoichi Nishimura*, Junsuke Shibata*, Akira Kawaguchi*, Masashi Kodama*

Department of Surgery, Komatsu Hospital
*The First Department of Surgery, Shiga University of Medical Science

When a 53-year-old man with dysphagea underwent barium esophagograms in our hospital, a filling defect of 8 cm in length was revealed at the Im to Ea regions of the esophagus. Endoscopy showed a protruding tumor with ulceration in the middle portion of the esophagus (37 cm distal to the incisors). The biopsy substantiated moderately differentiated squamous cell carcinoma. The resected specimen, showing the ulcerative and localized type, measured 7×5.5 cm, and invaded throught the adventitia. The histological findings of the specimen exhibited the solid and trabecullar pattern of basal cell-like small cell nests, which contained the components of the squamous cell carcinoma with cornified features in some portion. Thus the diagnosis was basaloid-(squamous) carcinoma of the esophagus, with a stagegrouping of a2 n2 M0P10, stage III. Despite postoperative recombinant chemotherapy of cisplatin and 5-fluorouracil, lung metastasis was noticed. Eventually the patient died of lung, liver and intraperitoneal lymph node metastases 8 months after surgery, in spite of chemotherapy and irradiation.

Key words
esophageal carcinoma, basaloid-(squamous) carcinoma

Reprint requests
Yutaka Nishida Department of Surgery, Komatsu Hospital
11-6 Kawakatsu, Neyagawa, 572 JAPAN

Accepted
April 5, 1995

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