A Case of Common Bile Duct Carcinoma Associated with Primary Biliary Cirrhosis

Daisuke Minabe, Akira Kubo, Masazumi Takahashi

Department of Surgery, Yokosuka Municipal Hospital

A case of primary biliary cirrhosis (PBC) complicated by common bile duct carcinoma is reported. A 50-year-old woman who had been treated medically for asymptomatic PBC for 7 years was hospitalized because of jaundice and skin itching. She was diagnosed as having obstructive jaundice,and underwent percutaneous transhepatic cholangiodrainage. Ultrasonography and computed tomography revealed a pancreas head tumor. On laparotomy, the tumor was found to have invaded the second portion of the duodenum, and pancreotoduodenectomy was performed. The histological findings indicated a welldifferentiated adenocarcinoma of the common bile duct. Although PBC complicated by malignancy is common, PBC complicated by common bile duct carcinoma is very rare. To our knownledge, there is no report of PBC with common bile duct carcinoma in Europe and the United States. Only one autopsy record of PBC with hilar bile duct carcinoma is available in Japan.

Key words
primary biliary cirrhosis PBC complicated by malignancy, common bile duct carcinoma

Reprint requests
Daisuke Minabe Department of Surgery, Yokosuka Municipal Hospital
1-3-2 Nagasaka, Yokosuka City, 240-01 JAPAN

Accepted
February 14, 1996

To read the PDF file you will need Abobe Reader installed on your computer.