Synchronous Squamous Cell Carcinoma of the Thoracic Esophagus and Hepatocellular Carcinoma

Goro Honda, Nobuyasu Yamasaki, Yasuyuki Shimahara*, Toyotake Okanoue, Tetsuya Uehara, Shigehiko Yagi, Toshiaki Kurakazu, Shinsuke Kajiwara, Toshihiko Sakao, Kenichi Kinoshita

Department of Surgery, Uwajima City Hospital
*First Department of Surgery, Ehime University School of Medicine

The patient was a 45-year-old man with liver cirrhosis accompanied by B type hepatitis who had been diagnosed as having synchronous squamous cell carcinoma of the thoracic esophagus (SCC) and hepatocellular carcinoma (HCC). For 2 months after admission, lipiodolization and transarterial embolization (TAE) for HCC was performed, and for SCC, cisplatin was given intravenously in 4 sessions and UFT^® was administered orally every day. As a result of these treatments, HCC was markedly curtailed without any tumor in the left lobe, but SCC was not abolished completely. Therefore, we performed stripping of the esophagus by blunt dissection and right hepatic lobectomy simultaneously. Histologically, SCC was diagnosed as moderately differentiated, invading the muscularis mucosa. As to the HCC, it was not possible to determine the type of differentiation, becuase most of the tumor tissues were necrotized due to the effect of previous TAE treatment. The patient tolerated the operation and the postoperative course was uneventful. After 9 months, three nodules of recurrent HCC were detected in the remnant liver. For these lesions percutaneous ethanol injection and TAE were performed and these streatments were effective in controling the growth of the lesions. The patient is now alive 22 months after the opeartion without further recurrence.

Key words
esophageal carcinoma, hepatocellular carcinoma, synchronous carcinoma

Reprint requests
Gorou Honda Department of Surgery, Uwajima City Hospital
1-1 Gotenmachi, Uwajima City, 798 JAPAN

Accepted
October 9, 1996

To read the PDF file you will need Abobe Reader installed on your computer.