CASE REPORT
A Case Report of Synchronous Triple Early Carcinomas in the Stomach, Papilla of Vater and Rectum
Sumiya Ishigami, Shoji Natsugoe, Masahiro Tokushige, Hironori Sakita, Kanetatsu Kimotsuki*, Takashi Aikou
First Department of Surgery, Kagoshima University School of Medicine
*Department of Surgery, Soo Gun Medical Association Hospital
We experienced a case of synchronous triple early cancers of the stomach, papilla of Vater and rectum. A 57-year-old man was admitted to the hospital because of detection of pancreatic cyst. Preoperative alimentary tract examination revealed a shallow depressed lesion of the stomach, a submucosal tumor-like bulge on the papilla of Vater and a protruding mass with a central ulceration in the upper rectum. Histopathologically each of the three lesions was identified as carcinoma. Total gastrectomy, pancreatoduodenectomy and low anterior resection were performed at the same time. The gastrointestinal tract was reconstructed with Roux Y, Child manner and direct end-to-end color-colostomy. The final pathological report indicated all three of the carcinomas were limited to the submucosa, and regional lymph nodes were negative for cancer. By immunohistochemical staining with anti-p53 monoclonal antibody, expression of p53 was detected in the rectal cancer lesion. The postoperative course was uneventful except for leakage of the pancreaticojejunostomy. The patient's condition is presently stable without signs of relapse. A case of simultaneously resected triple primary early cancer has rarely been reported, this is the second case reported in Japan.
Key words
triple primary carcinoma, early cancer
Jpn J Gastroenterol Surg 30: 769-773, 1997
Reprint requests
Sumiya Ishigami First Department of Surgery, Kagoshima University School of Medicine
8-35-1 Sakuragaoka, Kagoshima, 890 JAPAN
Accepted
October 9, 1996
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