So-called Carcinosarcoma of the Esophagus with Singular Growth Pattern, Report of a Case

Masaki Kitazono, Mario Shimada, Syouji Natsugoe, Naonori Ikeda, Masamichi Baba, Toshitaka Fukumoto, Takashi Aikou

First Department of Surgery, Faculty of Medicine Kagoshima University

Carcinosarcoma of the esophagus is classified as "so-called carcinosarcoma", "pseudosarcoma", and "true carcinosarcoma". We report "so-called carcinosarcoma" of the esophagus arising from the esophago/gastric (E-G) junction. A tumor with a short stalk was found at the E-G junction and was found to be hanging down into the stomach. In addition, the tumor had a singular gowth pattern, lobulated two portions. The pathological findings of "so-called carcinosarcoma" are characterized by sarcomatous parts with epidermal features. In this case, HE staining revealed that transition from squamous cell carcinoma of the stalk to sarcomatous cells, and we diagnosed "so-called carcinosarcoma". However, the sarcomatous cells stained with anti-vimentin antibody, a marker of the non-epidermal component, but not with anti-keratin and anti-EMA antibody, markers of the epidermal component. We must investigate about the discrepancy between the HE staining and the immunohistochemical staining of "so-called carcinosarcoma".

Key words
so-called carcinosarcoma

Reprint requests
Masaki Kitazono First Department of Surgery, Faculty of Medicine, Kagoshima University
8-35-1 Sakuragaoka, Kagoshima, 890 JAPAN

Accepted
March 19, 1997

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