Recurrence after Curative Resection of Submucosal Invasive Colorectal Carcinoma

Nobuhiro Tokunaga, Sotaro Sadahiro, Takashi Noto, Seiei Yasuda, Masaya Mukai, Hideki Ishida, Tomihiko Kimura, Toshiyuki Suzuki, Tomoo Tajima, Hiroyasu Makuuchi

Department of Surgery II, Tokai University School of Medicine

Of 51 patients who underwent curative resection of submucosal invasive colorectal carcinoma, four had tumor recurrences. Two primary tumors were located in the rectum and two in the sigmoid colon. The configuration of all the primary lesions was subpedunculated type. Three patients underwent subsequent transabdominal colonic resection after endoscopic polypectomy. One patient initially underwent transanal resection. Two had metastatic lymph nodes at the colonic resection. The histologic type of the primary carcinomas was well to moderately differentiated adenocarcinoma without undifferentiated carcinoma. One patient had recurrence in the liver only, one in the lung only, one lymph node recurrence only, and one had recurrences in multiple sites. Tumor location in the sigmoid colon and rectum, a subpedunculated polyp, and moderately differentiated adenocarcinoma are risk factors for recurrence of curatively resected submucosal invasive colorectal carcinoma.

Key words
submucosal invasive colorectal cancer, risk factors of recurrence, distal metastasis

Reprint requests
Nobuhiro Tokunaga Department of Surgery, Tokai University School of Medicine
Bohseidai, Isehara, 259-11 JAPAN

Accepted
October 1, 1997

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