Two Cases of Intrahepatic Cholangiocellular Carcinoma with Intraductal Extension into the Extrahepatic Bile Duct

Hideto Ochiai, Shoichi Hishinuma*, Jiro Nasu*, Jiro Ando*, Iwao Ozawa*, Junichi Matsui*, Takao Inada*, Hideaki Shimizu*, Kenjiro Kotake*, Yoshiro Ogata*

Department of Surgery, Tenryu National Hospital
*Department of Surgery, Tochigi Cancer Center

We experienced two cases of cholangiocellular carcinoma with intraductal extension into the extrahepatic bile duct. The first patient was a 46-year-old owman complaining of fatigability and appetite loss. Computed tomogram (CT) demonstrated a hepatic tumor in the medial segment with a mass in the common bile duct. Pericutaneous transhepatic cholangiogram revealed a filling defect in the common bile duct. Extended left hepatic lobectomy combined with bile duct resection was carried out. The resected specimen showed a nodular tumor arising from the medial segment of the liver with intraluminal extension into the common bile duct. Histologic section of the tumor showed mucin-producing cholangiocellular carcinoma. The second patient was a 62-year-old man. Ct showed a tumor in the lateral segment of the liver. Left hepatic lobectomy was performed. The resected specimen showed a nodular tumor with intraductal extension into the common hepatic duct. Histologic section of the tumor showed moderately differentiated cholangiocellular carcinoma. Intrahepatic cholangiocellular carcinoma with intraductal extension into the extrahepatic bile duct is uncmmon. In a review of literature, we could only one report that described a nodular tumor with intraluminal extension into the common bile duct.

Key words
cholangiocellular carcinoma, intraductal extension into the extrahepatic bile duct

Reprint requests
Hideto Ochiai Department of Surgery II, Hamanatsu Medical University
3600, Handa-cho, Hamamatsu, 431-3192 JAPAN

Accepted
May 19, 1998

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