A Case of Collision Tumor with Leiomyoblastoma and Gastric Cancer

Taihei Itoh, Yoshifumi Matsui, Kouichi Nagao^*, Tomotaka Awano, Haruo Satoh and Akio Sakamoto

Department of Surgery, Kokuho Narutoh Hospital
^*Department of Pathology, Ichihara Hospital of Teikyo University

There have been few reports of patients with leiomyoblastoma of the stomach in association with other malignancies of the alimentary tract. Moreover, a collision tumor with a leiomyoblastoma and cancer in the stomach is very rare. An 80-year-old man presented with a expirational dyspnea and hematemesis. Blood laboratory examinations showed severe anemia and malnutrition. Upper gastrointestinal radiography and an endoscopic examination revealed a submucosal tumor on the gross curvature of the gastric body and Borrmann type4 gastric cancer in the antrum. Tissue from an endoscopic biopsy histologically revealed a poorly differentiated adenocarcinoma. A diagnosis of a Borrmann type4 gastric cancer with a submucosal tumor of the stomach was subsequently confirmed. A subtotal gastrectomy was performed, and the histological findings of the Borrmann type4 gastric tumor revealed a pooly differentiated adenocarcinoma and a submucosal tumor leiomyoblastoma of clear cell type. In addition, the gastric tumor was located close to the capsule of the leiomyoblastoma but did not invade it. There was no admixture of the two cellular components, indicating that the tumors were of the collision type. The rarity of the collision phenomenon involving a gastric cancer and a leiomyoblastoma is apparent since there in only one documented case reported in the literature.

Key words
collision tumor, leiomyoblastoma of stomach, gastric cancer

Reprint requests
Yoshifumi Matsui The Second Department of Surgery, Chiba University, School of Medicine 1-8-1 Inohana, Chuo-ku, Chiba City, 260-8677 JAPAN

Accepted
November 13, 1998

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