A Case of Gastrointestinal Stromal Tumor of Duodenum

Yoshihiro Kitayama, Yasuhumi Fukuda, Sintarou Eziri, Rikitosi Ueno, Syusaku Habu, Keniti Wakasa¹⁾ and Motohiko Suguro²⁾

Department of Surgery, and Department Pathology¹⁾, Isinkai Yao-polyhospital Digestive-center, Suguro Hospital²⁾

A gastrointestinal stromal tumor (GIST) of the duodenum in a 56-year-old woman, detected by gastric endoscopy, is reported. The examinations revealed a hemispheric submucosal tumor, 3 cm in diameter with delles and a bridging fold. Gastrectomy was performed. Histological findings of the resected specimen showed that the tumor was composed of spindle cell proliferation. Immunohistochemically, the tumor cells was negative for smooth muscle antigen and S-100 protein, but was positive for vimentin. The mitotic index was 1∼3/10 high power fields. The concept of GIST has not yet been established, and so we reported this case with consideration of the literature.

Key words
gastrointestinal stromal tumor, immunohistochemistry, submucosal tumor

Reprint requests
Yoshihiro Kitayama Department of Surgery, Isinkai Yao-polyhospital Digestive-center 1-41, Numa, Yao-city, 581-0036 JAPAN

Accepted
December 9, 1998

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