Clinicopathological Study of Multiple Cancer with Gastric Cancers

Masayuki Hirokawa^{1) 2)}, Ichiro Honda¹⁾, Satoshi Watanabe¹⁾ and Yoshihiro Fujita¹⁾

¹⁾Department of Gastrointestinal surgery, Chiba Cancer Center, ²⁾Department of Surgery II, Kochi Medical School

We treated 2642 patients with gastric cancer in Chiba Cancer Center. Of these patients, 152 (5.8%) had malignant neoplasma in other organs. There were 44 cases of synchronous cancers, 52 cases of metachronous cancers prior to gastric cancer (Prior group) and 56 cases of metachronous cancers after gastric cancer (Later group). The primary malignant neoplasmas associated with gastric cancers originated in the large bowel (36 cases), oral cavity & pharynx & larynx (21 cases), kidney & urinary tract (15 cases) and other organs. Cancer of a digentive system organ was noted in the Synchronous and Prior group. The cumulative 5-year survival rates were 28.1% in the metachronous group, 79.4% in the Prior group and 52.3% in the Later group. The prognosis of early gastric cancer was worse in the Synchronous group and that of advanced gastric cancer was better in the Prior group. In order to investigate multiple primary cancers, it is necessary to classify multiple cancers by the duration beetween gastric cancer and malignant neoplasmas detected at other organs operations.

Key words
multiple cancer, gastric cancer, family history, metachronous multiple cancer, synchronous multiple cancer

Reprint requests
Masayuki Hirokawa Department of Surgery II, Kochi Medical School Kohasu, Oko-cho, Nankoku, 783-8505 JAPAN

Accepted
January 27, 1999

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