CASE REPORT
A Case of Hereditary Non-polyposis Colorectal Cancer (HNPCC) Associated with Leiomyosarcoma of the Trapezius Muscle
Kunio Takeuchi, Yasushi Tsuzuki, Tetsu Ando, Masanori Kobayashi, Ryokuhei Manda and Tatsuhito Nouchi
Department of Surgery, Tone Chuo Hospital
We report a case of HNPCC associated with leiomyosarcoma of the trapezius muscle. A 55-year-old man had ascending colon cancer at 24 years of age, transverse colon cancer at 35 years and sigmoid colon cancer at 54 years. His mother had colon cancer, his father had gastric cancer, two of his brothers had colon cancer, one brother had liver cancer, and his uncle and his cousin on his mother's side had colon cancer. He visited a clinic due to a swelling of his right shoulder. Aspiration cytology was performed and a diagnosis of class V was made. Thereafter, he consulted and was admitted to our department. After detailed examination, he was diagnosed as having a malignant tumor of the trapezius muscle, and the tumor was surgically removed. Histopathological diagnosis of the excised specimen was leiomyosarcoma originating from the trapezius muscle. He died of local recurrence and lung metastases 4 months after surgery. One of the clinical features of HNPCC is a high incidence of multiple primary neoplasms although a few cases have been associated with malignant neoplasms of the soft tissues as in our case.
Key words
hereditary non-polyposis colorectal cancer, leiomyosarcoma of the trapezius muscle
Jpn J Gastroenterol Surg 32: 2153-2157, 1999
Reprint requests
Kunio Takeuchi Department of Surgery, Tone Chuo Hospital 1855-1 Higashiharashin-machi, Numata-city, 378-0053 JAPAN
Accepted
March 31, 1999
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