Study on the Mode of Lymph Node Metastasis of Colorectal Cancer not Infiltrating Serous Membrane (Outer Membrane)

Toru Tezuka, Mamoru Suzuki, Yuji Inoue, Katsutoshi Yoshida and Ken Takasaki

Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University

150 patients with colorectal cancer not infiltrating serous membrane (outer membrane) were devided into two groups of patients on the basis of tumor-occupying rates in the most distant positive lymphnodes; 77 patients (mild type) who had tumor-occupying rate of less than 50% and 73 patients (massive type) of 50% or more. Statistical significance between the two groups was seen in the rate of poorly differentiated adenocarcinoma and mucinous carcinoma, the number of metastatic lymphnode (3. 4 nodes vs 2. 0), and the maximal diameter of metastatic lymphnode (9. 2mm vs 5. 7). Postoperative recurrence of the lymphnodes occurred in 2 of the 77 patients with mild types (2. 6%) and in 17 of the 73 with massive types (23. 3%). Lymphonde recurrence free cumulative five-year survival rate was statistically higher in mild type than in massive type (97. 3% vs 73. 4%), and statistical significance was also seen in the patients with n₁ (+) (96. 6% and 76. 5%) and n₂ (+) (100% and 64. 3%). Those data show that tumor-occupying rates in most distant postive lymphnodes can predict postoperative lymphnode recurrence.

Key words
colorectal cancer not infiltrating serous membrane (outer membrane), lymphnode metastasis, lymphnode recurrence, tumor-occupying types

Reprint requests
Toru Tezuka Institute of Gastroenterology, Tokyo Women's Medical University 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666 JAPAN

Accepted
April 28, 1999

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