Recurrence after Curative Resection of Submucosal Invasive Colorectal Cancer

Yuji Inoue, Mamoru Suzuki and Ken Takasaki

Department of Surgery, Institute of Gastroenterology, Tokyo Women's Medical University

Of 104 patients who underwent curative resection for submucosal invasive colorectal cancer in our institution from 1988 to 1997, 6 patients (5.8%) had tumor recurrence, and 4 patients (3.9%) had local and lymph node recurrence. Of the four patients, the tumors were located in the rectum in 3, and in the descending colon in 1. Histopathological study revealed that 3 patients had moderately differentiated tubular adenocarcinoma and one had well differentiated tubular adenocarcinoma. Three had lymph node metastasis. All 4 patients who had local and lymph node recurrence had lymph vessel invasion. The Depth of cancer invasion was sm3 in these 4 patients. In addition, local and lymph node recurrence occurred higher in the patients who had moderately differentiated tubular adenocarcinoma, lymph node metastasis and lymph vessel invasion. Among the 106 patients, 2 (1.9%) had solitary liver metastasis, and partial hepatic resection was performed with no evidence of recurrence. Liver metastasis was not observed to be a risk factor in this histopathological study of submocasal invasive colorectal cancers.

Key words
colorectal submucosal invasive cancer, local and lymph node recurrence, liver metastasis

Reprint requests
Yuji Inoue Insitute of Gastroenterology, Tokyo Women's Medical University 8-1 Kawada-cho, Shinjuku-ku, Tokyo, 162-8666 JAPAN

Accepted
May 25, 1999

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