A Case of Primary Squamous Cell Carcinoma of the Liver

Hisaya Azuma, Naoki Yokoo, Tatsushi Kato, Takami Fukui, Tetsuya Yamaguchi and Kiyohisa Okamoto^*

Department of Surgery and Department of Pathology^*, Takayama Red Cross Hospital

A 58-year-old man was admitted to the hospital because of epigastralgia. Elevated levels of the biliary enzymes were noted, but tumor markers and markers for hepatitis viruses were negative. A CT scan demonstrated a low density mass with an unclear margin in segment 4 of the liver. T1 MRI showed a low signal mass and a high signal mass in T2. Angiography revealed a lightly stained tumor area. A left lobectomy of the liver was performed. The tumor was 4.5×3×3 cm, not encapsulated but with a clear margin, and the section was yellowish white in color. Pathologically, it was a well differentiated squamous cell carcinoma with keratinization and did not contain any adenocarcinoma component. There was not a finding of inflammation or fibrosis in the background liver tissue. The patient has been well without any signs of recurrence for 21 months after the operation.

Key words
liver tumor, squamous cell carcinoma

Reprint requests
Hisaya Azuma Department of Surgery, Takayama Red Cross Hospital, 3-11 Tenman-machi, Takayama-shi, 506-8550 JAPAN

Accepted
October 26, 1999

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