Estimation of ICG-R₁₅ from the parameters of ^99m Tc-GSA liver scintigraphy and application for hepatectomy

Shinjiro Tomiyasu¹⁾, Masahiko Hirota¹⁾, Hisami Ohsima²⁾, Yuji Sakamoto³⁾, Katumi Yamazaki²⁾ and Michio Ogawa¹⁾

Department of Surgery II, Kumamoto University Medical School¹⁾, Department of Surgery²⁾ and Radiology³⁾, Arao City Hospital

The measurement of the clearance of indocyanine green (ICG) has been widely used for the indication and the selection of operative procedures when patients with chronic hepatitis and/or liver cirrhosis are undergoing hepatic resection.
The ICG clearance, however, is greatly influenced when patients are suffering from portocaval shunt.
Based on the data from 169 patients, the formulas for conversion of the parameters of ^99mTc-galactosyl human serum albumin liver scintigraphy to ICG-R₁₅ were established. The formulas are as follows.
ICG-R₁₅=105-LHL₁₅×101
ICG-R₁₅=HH₁₅×87-31
These formulas are useful for the selection of treatment strategy, especially for patients with portocaval shunt.

Key words
asialoglycoprotein,^99mTc-galactosyl human serum albumin, indocyanine green, portocaval shunt, hepatectomy

Reprint requests
Michio Ogawa Department of Surgery II, Kumamoto University Medical School 1-1-1 Honjo, Kumamoto-city, 860-8556 JAPAN

Accepted
January 26, 2000

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