Gastric Submucosal Myxoid Change with Solitary Gastric Gland Heterotopia

Masayuki Okido¹⁾³⁾, Masato Kato¹⁾, Takashi Matsuura²⁾, Hitoshi Ichimiya¹⁾, Mitsuru Nakagaki¹⁾ and Takashi Yao⁴⁾

Department of Surgery¹⁾ and Radiology²⁾, Hamanomachi Hospital Department of Surgery and Oncology³⁾, and Anatomic Pathology⁴⁾ Graduate School of Medical Sciences, Kyushu University

Myxoid changes in the stomach are extremely rare. We report a case of solitary gastric gland heterotopia with myxoid change associated with submucosal tumor. A 54-year-old man admitted to hospital to investigate an elevated gastric lesion undergoing an upper gastrointestinal series and gastroendoscopic examinations was found to have a gently elevated lesion with a shallow depression on the surface of the posterior wall of the upper gastric body. Macroscopic findings of the resected sample showed a well-defined jelly-like mass in the submucosal layer. Microscopic findings showed myxoid tissue, confined to the submucosa, surrounded by cystically dilated heterotopic glands. Pathogenesis is unknown but may be associated with repeated inflammatory change in mucosa. No reports have been made, to our knowledge, on myxoid change in the heterotopic gland, making our case of particular pathological interest. Such unique lesions should thus be considered when diagnosing submucosal gastric tumors.

Key words
gastric gland heterotopia, myxoid change, submucosal tumor

Reprint requests
Masayuki Okido Department of Surgery, Hamanomachi Hospital 3-5-27 Maizuru, Chuo-ku, Fukuoka, 810-8539 JAPAN

Accepted
July 25, 2000

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