A Case of Synchronous Xanthogranuloma of Stomach and Gallbladder

Junji Okayama, Kazutaka Matsumura, Seiichi Sugihara, Naoyuki Nakatsuji, Takashi Nishiwada, Masato Horikawa and Hiroshige Nakano^*

Department of Surgery, Hoshigaoka Kouseinenkin Hospital, First Department of Surgery, Nara Medical University^*

A 59-year-old man referred to our hospital for 2 gastric submucosal tumors on the fornix and the lesser curvature of the lower body, revealed by upper gastrointestinal endoscopy, was found by abdominal ultrasonography and computed tomography to have chronic cholecystitis and adenomyomatosis of the gallbladder containing sludge. Operative findings showed a diffuse fibrous adhesion in the upper abdomen, especially around the gastric lesions and gallbladder. The gallbladder wall adhered to the duodenum. Intraoperative pathological diagnosis of the 2 gastric lesions was nonmalignant xanthogranuloma. Proximal gastrectomy combined splenectomy, wedge resection of the lesser curvature of the lower body, cholecystectomy, and pyroloplasty. Histologically, tumors were granulomatous, showing proliferation of foamy and inflammatory cells. Xanthogranuloma develops in a variety of organs, but synchronous xanthogranuloma of the stomach and gallbladder is rare. Further follow-up is believed necessary because of cancer reported in cases of xanthogranuloma of the stomach or gallbladder.

Key words
synchronous xanthogranuloma, stomach, gallbladder

Reprint requests
Junji Okayama First Department of Surgery, Nara Medical University 840 Shijo-cho, Kashihara, 634-8522 JAPAN

Accepted
September 20, 2000

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