Correlation of CEA Doubling Time with Survival of Patients who Developed Liver Metastasis from Colorectal Cancer

Sakae Miyamoto, Sadao Anazawa and Yoji Yamazaki

Department of Surgery, The Jikei University School of Medicine

Following the initial CEA increase after primary resection in patients with colorectal cancer, the correlation between CEA doubling time and survival was examined in the patients who developed liver metastasis but received no further treatment (n=15). There was a significant correlation between the two (correlation coefficient r=0.7754). The mean survival after the initial CEA increase expressed in multiples of the individual CEA doubling times was 8.5±3.1. The survival of patients who developed liver metastasis from colorectal cancer after primary resection but received no further treatment can be presumed if the CEA doubling time is measured.

Key words
hepatic metastasis, colorectal cancer, CEA doubling time

Reprint requests
Sakae Miyamoto Department of Surgery, The Jikei University School of Medicine 3-25-8, Nishi-shinbashi, Minato-ku, Tokyo, 105-8461 JAPAN

Accepted
October 31, 2000

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