Colon Carcinoma in Crohn's Disease: A Case Report

Tadashi Kagaya, Yoshiyuki Shimamura, Masanori Ishii, Osamu Yoshitake, Shougo Fujita, Satoru Takayama, Masayuki Kougo and Motoki Nagai

Department of Surgery, Chibanishi General Hopital

We treated a 56-year-old woman with ascending colon cancer associated with subclinical Crohn's disease. She admitted for postprandial right lower abdominal pain. A fist-size mass palpable in the right lower abdominal quadrant was shown by the colonoscopic examination to be a stenotic lesion in the ascending colon. Right hemicolectomy was conducted based on a diagnosis of colon cancer. The lesion had regional mucosal erosion, a longitudinal ulcer, and cobblestone appearance without the polypoid fungating mass usually associated with right colon cancer. Microscopic findings showed a well-differenciated adenocarcinoma with mucinous components and noncaseating epithelioid cell granuloma, indicating this colon cancer was associated with subclinical Crohn's disease. Given the increase in Crohn's disease in Japan, the risk of colorectal carcinoma in patients with Crohn's disease should be borne in mind.

Key words
colon cancer, Crohn's disease, carcinigenesis

Reprint requests
Tadashi Kagaya Department of Surgery, Chibanishi General Hospital 107-1 Kanegasaku, Matsudo, 270-2251 JAPAN

Accepted
March 28, 2001

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