A Case of Undifferentiated Carcinoma of the Gallbladder Associated with Anomalous Arrangement of the Pancreaticobiliary Duct

Kaname Ishii, Shigehiro Tanaka, Takashi Nakamura and Tadashi Sasaki

Department of Surgery, Kouseiren Namerikawa Hospital, Namerikawa, Toyama

We report a case of resected undifferentiated carcinoma of the gallbladder with anomalous arrangement of the pancreaticobiliary duct. A 42-year old man was diagnosed with a tumor projecting into the gallbladder by ultrasonography and computed tomography. Anomalous arrangement of the pancreaticobiliary duct without dilation of the biliary duct was observed by endoscopic retrograde cholangiopancreatography. Abdominal angiography showed a hypervascular tumor, necessitating cholecstectomy with resection S4a+S5 of the liver, resection of the extrahepatic common bile duct, lympadenectomy, and hepaticojejunostomy. The tumor was 3.5×2.5 cm and presented macroscopically as a nodular. Histology showed atypical tumor cells and a diagnosis of undifferentiated gallbladder carcinoma. The clinical stage was si, hinf1a, binf0, pv0, a0, bm0, hm0, stageIVa. Immunohistologically, EMA, cytokeratin, CA19-9, and CEA stains were positive but vimentin and AFP stains were negative.

Key words
gallbladder carcinoma anomalous arrangement of the pancreaticobiliary duct

Reprint requests
Kaname Ishii Department of Surgery II,School of medicine, Kanazawa University 13-1 Takara-machi, Kanazawa, 920-8641 JAPAN

Accepted
June 26, 2001

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