A Resected Case of the Primary Duodenal Adenocarcinoma Associated with von Recklinghausen's Disease

Takenari Nakata, Takehiko Sakai, Toshinari Kumaki and Nobuki Sakaguchi^*

Department of Surgery, Nagano Matsushiro General Hospital Department of Pathology, Shinshu University School of Medicine^*

We report a primary duodenal adenocarcinoma associated with von Recklinghausen's disease (VRD). A 64-year-old woman visiting our hospital due to appetite loss and epigastralgia in April 1999 was diagnosed with nonampullary primary duodenal cancer in radiological studies, upper gastrointestinal endoscopy and histological diagnosis. We conducted pancreatoduodenectomy. Histological examination showed moderately differentiated adenocarcinoma. Tumors of the neural crest origin are known to occur frequently in patients with VRD. The concurrence of intestinal cancer in this present case, however, is very rare in the Japanese literature.

Key words
von Recklinghausen's disease, primary duodenal adenocarcinoma

Reprint requests
Nakata Takenari Department of Surgery, Nadano Matsushiro general hospital 183 Matsudhiro, Matsushiro-town, Nagano-city, 381-1231 JAPAN

Accepted
July 30, 2001

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