A Long Survival Case of Carcinoid Tumor of the Gallbladder

Shigeru Hibino, Susumu Fujioka, Kenji Kato, Yuuichi Machiki, Yasushi Kutsuna, Yasushi Takenouchi, Jyunichi Takamizawa, Daisuke Takara and Katsue Yoshida^*

Department of Surgery and Pathology^*, Kiryu Kousei General Hospital

Our long survival case is aggressive neoplasm, despite the histological diagnosis as carcinoid of the gallbladder. Case: A 61-year-old woman with right upper quadrant pain was found in ultrasonography (US) and computed tomography (CT) to have a tumor surrounding the gallbladder. Under a preoperative diagnosis of gallbladder adenocarcinoma, we conduced right liver lobectomy of the liver. Microscopically, the tumor showed a carcinoid tumor consisting of nests of small oval cells with round to oval nuclei. Tumor cells were positive for Grimelius'stain. Immunohistochemically, these cells were positive for chromoganinA. Although hepatic metastasis, right renal metastasis, abdominal paraaortic lymph node metastasis, and right adrenal metastasis were detected after the operation, aggressive therapy led to 81 months (6.5 years) of survival.

Key words
carcinoid tumor, gallbladder, endocrine cell carcinoma

Reprint requests
Shigeru Hibino Department of Surgery and Pathology^*, Kiryu Kousei General Hospital, 6-3 Orihime-machi, Kiryu, 376-0024 JAPAN

Accepted
December 12, 2001

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