Resected Case of Hepatobiliary Cystadenoma with Ovarian-Like Stroma

Taku Iida, Kentaro Yamagiwa, Shintaro Yagi, Koji Fujii, Takashi Hamada, Shugo Mizuno, Masami Tabata, Hajime Yokoi, Shuji Isaji and Shinji Uemoto

First Department of Surgery, Mie University

We report a 30-year-old woman who, in 1991, experienced epigastric pain for which abdominal ultrasonography (US) and computed tomography (CT) showed a cystic lesion about 3.5cm in diameter in the lateral hepatic segment. When the lesional diameter increased to 11cm in 1996, the lesion was injected with minocycline. In 1998, CT showed that the cyst had increased to 6.5cm in diameter, forming a thick wall and septum within. Based on a preoperative diagnosis of hepatobiliary cystadenoma or cystadenocarcinoma, we conducted lateral segmentectomy. The resected specimen contained a multilocular 7.5× 6× 4cm lesion. Histological examination showed densely cellular stoma composed of ovarian-like stroma, findings consistent with hepatobiliary cystadenoma with mesenchymal stroma (CMS). The ovarian-like stroma stained positive immunohistochemically for antibodies to ER and PgR. Although CMS is considered to have a good prognosis, we recommend aggressive surgical resection due to its malignant potential.

Key words
hepatobiliary cystadenoma, ovarian-like stroma

Reprint requests
Taku Iida First Department of Surgery, Mie University 2-174 Edobashi, Tsu-shi, 514-8507 JAPAN

Accepted
September 25, 2002

To read the PDF file you will need Abobe Reader installed on your computer.