A Case of Localized Primary Sclerosing Cholangitis

Jun Suzuki, Ikuo Nagashima, Masatoshi Shiratori, Taihei Koide, Miki Adachi, Tetsuo Imamura^*, Junji Shiga^*and Kota Okinaga

Department of Surgery and Department of Pathology^*, Teikyo University School of Medicine

A 68-year-old man admitted for jaundice was found in cholangiography by pericutaneous transhepatic gallbladder drainage tube to have a narrowed segment in the common hepatic duct. We suspected bile duct carcinoma and conducted cholecystectomy, resection of the narrowed segment of the upper portion of the bile duct, and hepaticojejunostomy (Roux-en-Y). Histopathological examination of the resected specimen showed no malignancy, but periductal fibrosis with severe infiltration of chronic inflammatory cells, diagnosed as primary sclerosing cholangitis (PSC). The patient has remained in good health in the 8 months since surgery. Reviewing other reported cases, localized PSC such as our case appeared to be a clinical entity different from typical PSC, which has diffuse, multiple strictures of the biliary tree.

Key words
primary sclerosing cholangitis, bile duct cancer, obstructive jaundice

Reprint requests
Jun Suzuki Department of Surgery, Teikyo University School of Medicine 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8605 JAPAN

Accepted
November 27, 2002

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