Usefulness of Orally Administered Own Bile and Inchin-ko-to for the Prolonged Obstructive Jaundice -Report a Case-

Fuminori Goda, Ken Ishimura, Kunihiko Izuishi, Keiich Okano, Yukihiko Karasawa, Hisashi Usuki and Hajime Maeta

First Department of Surgery, Kagawa Medical University

A 65-year-old man with lower bile duct cancer was treated by percutaneous transhepatic biliary drainage (PTBD) for obstructive jaundice, but reduction was poor with a bile discharge of 120ml/day and a bilirubin reduction rate b of -0.0189 up to 4 weeks after PTBD. We diagnosed the patient as having prolonged obstructive jaundice. Own bile and Inchin-ko-to was orally administered, and jaundice improved dramatically. Bile discharge was 410ml/day and bilirubin reduction rate b -0.0504 at 7 weeks after PTBD. After undergoing radical pancreaticodoudenostomy, he was discharged after smooth postoperative course. Recent studies showed that Inchin-ko-to inhibits the apoptosis of hepatocytes resulted from bile congestion after obstructive jaundice, and lt induces rapid recovery of liver function. Inchin-ko-to is therefore useful in bile duct drainage.

Key words
prolonged obstructive jaundice, percutaneous transhepatic biliary drainage (PTBD), Inchin-ko-to

Reprint requests
Fuminori Goda First Department of Surgery, Kagawa Medical University 1750-1 Ikenobe, Miki, Kita, Kagawa, 761-0793 JAPAN

Accepted
November 27, 2002

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