Early Gastric Cancer Associated with Submucosal Heterotopic Gastric Glands, Preoperatively Diagnosed as Advanced Stage

Keigo Okada, Shigehiro Kikuyama, Yoshihiro Imazu, Rempei Ohyama, Hideki Orikasa^* and Kazuto Yamazaki^*

Departments of Surgery and Pathology^*, Saiseikai Central Hospital

A 56-year-old man admitted for gastric cancer found in mass screening was found in endoscopy to have a 2 cm elevated lesion resembling a submucosal tumor with a type IIc-like depression on the posterior wall of the upper and middle stomach. A biopsy specimen showed adenocarcinoma. We preoperatively diagnosed the lesion as type IIa+IIc advanced cancer and conducted distal gastrectomy. The pathological diagnosis was well-differentiated adenocarcinoma extending to the submucosal layer with submucosal heterotopic gastric glands. The pathogenesis of the lesion was mainly explained by acquired aberration. Several reports about the relationship between lesions and cancer have been presented, but the issue remains controversial.

Key words
submucosal heterotopic gastric glands, early gastric cancer

Reprint requests
Keigo Okada Department of Surgery Saiseikai Central Hospital 1-4-17 Mita, Minato-ku, Tokyo, 108-0073 JAPAN

Accepted
May 27, 2003

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