Preoperative Evaluation of Hepatic Function Reserve by Converted ICGR₁₅ Calculated from ^99mTc-GSA Scintigraphy

Hideki Kawamura, Toshiya Kamiyama, Nobuaki Kurauchi, Takahito Nakagawa, Hirofumi Kamachi, Ryouji Yokoyama, Takeaki Kudo, Tatsushi Shimokuni, Michiaki Matsushita and Satoru Todo

Department of General Surgery, Hokkaido University Graduate School of Medicine

Purpose: To improve the accuracy of correlation between converted ICGR₁₅ from ^99mTc-GSA Scintigraphy (LHL15, HH15) and ICGR₁₅, we searched for the formula based on the characteristic of LHL15 and HH15. Materials and Methods: Preoperative hepatic function reserve was evaluated by converted ICGR₁₅, calculated with a formula acquired from the correlation between HH15 and ICGR₁₅, or the correlation between LHL15 and ICGR₁₅. Subjects were 144 patients undergoing hepatectomy after ^99mTc-GSA scintigraphy and indocyanine green retention test from June 1995 to September 2002. Results: Based on the fact that LHL15 is correlated with ICGR₁₅ in cases with better hepatic function reserve, and HH15 is correlated with ICGR₁₅ in cases with poorer hepatic function reserve. Two separate formulas were found in Liver Damage A and Liver Damage B to improve the correlation coefficient. ICGR₁₅=114−108×LHL15 was found in cases with Liver Damage A, and ICGR₁₅=−41+103×HH15 in cases with Liver Damage B. Conclusion: ICGR₁₅ converted from these formulas related better to ICGR₁₅ than that from the formula acquired from all cases.

Key words
hepatic functional reserve, hepatic resection, GSA scintigraphy

Reprint requests
Hideki Kawamura Department of General Surgery, Hokkaido University Graduate School of Medicine
N15W7, Kita-ku, Sapporo, 060-8638 JAPAN

Accepted
July 23, 2003

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