A Case of Primary Malignant Esophageal Lymphoma Responding to Chemoradiation Therapy

Kazuhiro Imai, Satoru Motoyama, Reijiro Saito, Manabu Okuyama, Hiroshi Imano, Taku Nakagawa, Masato Sageshima* and Jun-ichi Ogawa

Department of Surgery and Division of Clinical Pathology*, Akita University School of Medicine

We report a case of primary malignant esophageal lymphoma responding to chemo-radiation therapy. A 42-year-old man admitted for dysphagia was found in esophagography and gastrointestinal fiberscopy to have a 4 cm long smooth round stenosis without an irregular mucosal pattern in the middle thoracic esophagus. Computed tomography showed diffuse invasion to the main left bronchus and descending aorta. Diagnosis could not be made from endoscopic biopsy. Video-assisted thoracoscopic biopsy was conducted to confirm histology. The pathological diagnosis was diffuse large cell B lymphoma. Radiotherapy with a total dose of 40 Gy and CHOP chemo-therapy were administered. After treatment, no thoracic tumor was observable in CT. The patient is doing well, with no evidence of recurrence 3 years.

Key words
malignant lymphoma, esophagus, chemo-radiation therapy

Reprint requests
Kazuhiro Imai Department of Surgery, Akita University School of Medicine
1-1-1 Hondo, Akita City, 010-8543 JAPAN

Accepted
June 30, 2004

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