A Case of IIc Type Early Gastric Cancer Associated with Eosinophilic Granuloma Produced by Gastric Anisakiasis

Katsunori Saito, Hideaki Hashida, Nozomu Iwashiro, Masanori Ohara, Masanori Ishizaka, Satoshi Kondo* and Hiroyuki Kato*

Department of Surgery, National Hakodate Hospital
Division of Cancer Medicine, Cancer Medicine, Surgical Oncology, Hokkaido University Graduate School of Medicine*

A 77-year-old man had a history of gastric ulcer, for which he used an H2-blocker. In September 2002, early gastric cancer was detected during a periodical endoscopic examination. Distal gastrectomy was performed, and the resected specimen showed a type IIc tumor about 0.8×0.8 cm on the posterior wall in the greater curvature side of the antrum. Histological finding disclosed papillary adenocarcinoma and invasion was limited only to the sub mucosa. In the microscopic preparation there was found an eosinophilic granuloma beneath the carcinoma lesion, and a worm body was seen surrounded by necrotic substances. Only 20 cases of compound gastric cancer and Anisakiasis have been reported in Japan, so that any definite relation between both lesions remains obscure. We must be aware of the possibility that the Anisakiasis preferentially infested the cancerous mucosa, and carefully discriminate between cancer and eosinophilic granuloma produced by Anisakiasis.

Key words
gastric cancer, gastric Anisakiasis

Reprint requests
Katsunori Saito Division of Cancer Medicine, Cancer Medicine, Surgical Oncology, Hokkaido University Graduate School of Medicine
North15-West7, Kita-ku, Sapporo, 060-8638 JAPAN

Accepted
June 30, 2004

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