A Case Report of Colon Cancer with Multiple Liver Metastases Successfully Treated by Hepatic Arterial Infusion Chemotherapy of 5-FU, l-LV, CPT-11 and Hepatic Resection

Yasuo Kabeshima, Atsuko Tano, Noriaki Kameyama, Atsushi Toizumi, Yoichiro Tamura and Takahisa Kageyama

Department of Surgery, Kasumigaura Medical Center

A 54-year-old Japanese man with cecal cancer and multiple liver metastases (CEA: 95.0 ng/ml) who underwent ileoceal resection followed by implantation of hepatic arterial infusion was treated postoperatively with 5-fluorouracil, leucovorin, and irinotecan hydrochloride. Since metastatic liver lesions all shrunk markedly after 6 Kur of chemotherapy (CEA: 10.6 ng/ml), and no other metastatic lesion was seen, we resected the liver tumors. He remained alive for 14 months after the first operation. This case is rare in having multiple metastasis of colorectal cancer controlled by radical surgery, and chemotherapy with 5-FU, l-LV, and CPT-11.

Key words
hepatic arterial infusion chemotherapy, colon carcinoma, liver metastasis

Reprint requests
Yasuo Kabeshima Department of Surgery, Kasumigaura Medical Center
2-7-14 Shimotakatsu, Tsuchiura-shi, 300-8585 JAPAN

Accepted
June 30, 2004

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