A Case of Multifocal Gastric Cancer Detected by the Sign of Leser-Tré lat

Naruhiko Sawada, Jyunko Honda, Taeko Nagao, Jyunichi Seike and Atushi Umemoto

Department of Oncological and Regenerative Surgery, Tokushima University, School of Medicine

The sign of Leser-Tré lat is defined as seborrheic keratosis with pruritus characterized by rapidly increasing size and number. We report a case of multifocal early gastric cancer detected by the sign of Leser-Tré lat in the neck and chest. An 80-year-old man seen at the department of dermatology for rapidly spreading pruritus with and cervix and chest itching was suspected of the sign of Leser-Tré lat, necesictating upper gastrointestinal endoscopy that indicated early gastric cancer. The distal gastrectomy specimen showed three independent early cancer foci. The man continues to be well and relapse free 4 years after surgery. Seborrheic keratosis characterized by pruritus rapidly increasing size and number should lead diagnosticians to suspect the sign of Leser-Tré lat and the possible existence of visceral organ malignancies.

Key words
Leser-Trélat sign, multifocal cancer

Reprint requests
Naruhiko Sawada National Hospital Organization Zentsuji National Hospital
2-1-1 Senyuucho, Zentsuuji city, 765-8507 JAPAN

Accepted
July 28, 2004

To read the PDF file you will need Abobe Reader installed on your computer.