A Case of Multiple Liver Metastasis from Rectal Cancer Effectively Treated with Hepatectomy after Hepatic Arterial Infusion Chemotherapy

Fumihiro Taniguchi¹⁾²⁾, Katsuya Deguchi¹⁾, Tetsuro Yamashita¹⁾, Kazuma Koide¹⁾, Yasuhiro Shioaki¹⁾, Eito Ikeda¹⁾²⁾, Fumitaka Mutoh¹⁾, Hideaki Kurioka¹⁾, Yoshihito Takeuchi³⁾ and Yohei Hosokawa⁴⁾

Department of Surgery¹⁾, Department of Emergency and Critical Care Center²⁾, Department of Radiology³⁾ and Department of Anatomic Pathology Laboratory Medicine⁴⁾, Kyoto First Red Cross Hospital

A 64-year-old man undergoing Miles' operation for rectal cancer with multiple liver metastasis (a2, ly2, v3, n1, H3, P0, M0) in August 2001 underwent postoperative hepatic artery infusion (HAI) at 5 FU (1,500 mg /body/5 hr) weekly as an outpatient. HAI was done 46 times, with total 5 FU administered of 64 g. Metastatic tumors at S3, S4 and S6 disappeared but those at S5, 8 remained. The left hepatic artery narrowed and he hoped for hepatectomy. Neither distant metastasis nor local recurrence was detected, so he enderwent hepatectomy in July 2003. He continues to undergo HAI of 5 FU once a month as an outpatient. Hepatic resection after HAI chemotherapy is thus effective as a strategy in treating multiple liver metastasis from rectal cancer.

Key words
multiple liver metastasis from rectal cancer, hepatic arterial infusion chemotherapy, hepatectomy

Reprint requests
Fumihiro Taniguchi Department of Surgery or Emergency and Critical Care Center, Kyoto First Red Cross Hospita
l15-749 Honmachi, Higashiyama-ku, Kyoto, 605-0981 JAPAN

Accepted
October 19, 2004

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