A Case of Cholangiocarcinoma with Sarcomatous Change

Shogo Tokumaru, Hiroshi Hasegawa, Eiji Sakamoto, Shunichiro Komatu, Kiyotaka Kawai, Tomotake Tabata, Yasuyuki Fukami, Masatoshi Akita and Toyonori Tuzuki*

Department of Surgery and Department of Pathology*, Nagoya Daini Red Cross Hospital*

A 61-year-old man with epigastralgia and fever and found to have a liver tumor was found in dynamic CT to have a low-density tumor in the lateral segment and partly in the medial segment of the liver. The periphery was gradually irregularly enhanced. Tumor markers were within normal limits. Suspecting cholangiocarcinoma, we conducted left hepatic lobectomy with lymph node dissection on April 7 2003. Histopathological examination showed sarcomatous and tubular structures joined by a transitional form. We diagnosed it as cholangiocarcinoma with sarcomatous change. The patient had an uneventful postoperative course but died of liver metastases on January 15 2004. Cholangiocarcinoma with sarcomatous change is very rare. We report a case and review it in light of 13 reports in the Japanese literature.

Key words
cholangiocarcinoma, sarcomatous change, sarcomatoid cholangiocarcinoma

Reprint requests
Shogo Tokumaru Department of Surgery, Nagoya Daini Red Cross Hospital
2-9 Myoken-cho, Showa-ku, Nagoya, 466-8650 JAPAN

Accepted
November 30, 2004

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