A Case of Metachronous Metastasis to the Liver from Small Cell Carcinoma of the Stomach

Takuya Sugimoto, Tetsuya Kondo, Toyoo Nitta, Atsushi Yamamoto, Yutaka Ozeki and Yasutomo Sekido*

Department of Surgery and Department of Pathology*, Hospital Organization Shizuoka Medical Center

A 76-year-old man with a gastric abnormality detected in October 2001 had normal tumor markers in blood examination, but soluble IL-2 receptor of 926 U/ml. UGI and endoscopy showed a type 2 tumor in the antrum. Malignant lymphoma was counterindicated by biopsy, so total gastrectomy and splenectomy were conducted in December 2001. We diagnosed small cell carcinoma of the stomach by immunopathological and histopathological examination. Postoperative chemotherapy was conducted by CPT-11. Abdominal CT in August 2003 showed a tumor measuring 22 mm at S7 of the liver. No other recurrence was seen, so partial resection of S7S8 was conducted in November 2003. Histopathologicaly, we diagnosed metastatic small cell carcinoma from the stomach. Chemotherapy by VP-16 was done because of doubt of metastasis to the lung, and he is alive 3 years after gastrectomy and 1 year and 1 month after hepatectomy.

Key words
small cell carcinoma, endocrine cell carcinoma, metastasis to the liver from gastric carcinoma

Reprint requests
Takuya Sugimoto Department of Surgery, Hospital Organization Shizuoka Medical Center
762-1 Nagasawa, Shimizu-cho, Sunto-gun, 411-8611 JAPAN

Accepted
July 27, 2005

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