A Case of Primary Peritoneal Cystadenocarcinoma: Diagnosis, Treatment, and Clinical Course

Shojiro Kikuchi, Yoshitaka Nakamura, Tokunari Okayama, Hiroo Konishi, Yoshihiro Kitagawa, Tomoyuki Tagi, Toshiya Ochiai, Satoru Yasukawa* and Hisakazu Yamagishi

Department of Surgery and Division of Digestive Surgery, Department of Pathology*, Kyoto Prefectural University of Medicine

Peritoneal adenocarcinoma in peritoneum is rare, originating in the paramesonephric duct. An 80-year-old woman seen for diarrhea and abdominal pain was found in computed tomography (CT) to have a large intraabdominal mass. Preoperative diagnosis by CT, magnetic resonance imaging (MRI), and fluorodeoxyglucose-positron emission tomography (FDG-PET) indicated appendiceal cancer with peritoneal dissemination. The pathological diagnosis of the resected specimen was papillary adenocarcinoma of the ascending colon with mucinous cystadenocarcinoma and clear cell carcinoma. The woman underwent combined chemotherapy with CDDP/TS-1 for local recurrence. The prognosis of adenocarcinoma with clear cell carcinoma is generally dismal due to the poor response to chemotherapy. In this case, surgical resection and chemotherapy brought the recurrent tumor under control, thus indicating a new way of potentially managing such tumors.

Key words
cystadenocarcinoma, clear cell carcinoma, peritoneal

Reprint requests
Shojiro Kikuchi Department of Surgery, Kyoto Prefectural University of Medicine
465 Kajiicho, Kamigyo-ku, Kyoto, 602-8566 JAPAN

Accepted
January 25, 2006

To read the PDF file you will need Abobe Reader installed on your computer.