A Case of Solitary Splenic Metastasis from Ovarian Cancer

Masaki Ohi, Hiroyuki Fujikawa, Tohru Ohsawa, Takaaki Azuma, Hiroshi Koike, Tetsuya Miyake and Masato Kusunoki*

Department of Surgery, Okanami General Hospital
Department of Digestive and Pediatric Surgery, Mie University School of Medicine*

A 59-year-old woman with a history of operation and chemotherapy for ovarian cancer 9 years earlier was admitted for upper abdominal distension and appetiteloss in July 2001. Abdominal CT and MRI showed a tumor of the spleen. Serum CA125 had increased. Based on a diagnosis of solitary metastasis to the spleen from ovary or primary splenic tumor, we conducted surgery in August 2001. We found a tumor of the hilum of the spleen but no recurrence of ovarian cancer, and conducted splenectomy with resection of the diaphragm. The pathological diagnosis of the tumor was poorly differentiated adenocarcinoma metastatic from ovarian cancer. The patient remains alive 3 years and 10 months after splenectomy. Reports of solitary splenic metastasis from ovarian cancer are relatively rare. In some such cases, a good prognosis was obtained by chemotherapy following splenectomy, so splenectomy should be indicated in treating patients with solitary splenic metastasis from ovarian cancer.

Key words
solitary splenic metastasis, ovarian cancer

Reprint requests
Masaki Ohi Department of Digestive and Pediatric Surgery, Mie University School of Medicine
2-174 Edobashi, Tsu, 514-8507 JAPAN

Accepted
April 26, 2006

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