A Case of Neurinoma of Appendix

Hirohiko Satoh, Tomohiko Miyatani, Shinya Morimoto, Takahumi Kinoshita, Tsutomu Andoh and Junji Nagahori

Department of Surgery, National Hospital Organization Kochi National Hospital

A 70-year-old woman was admitted to our hospital with a chief complaint of feeling a tumor in her abdomen. Surgery was performed on suspicion of a tumor of the right ovary, and a mass measuring 8×6×6 cm was found distal in the appendix with no adhesions to surrounding tissue. Appendectomy was performed for a diagnosis of gastrointestinal stromal tumor, myoma, or neurinoma by frozen section. The tumor consisted of mesenchymal cells that exhibited anisocytosis but no mitoses. Immunohistochemically the cells were positive for S-100, but negative for α-SMA, CD-34, and c-kit, and the final diagnosis was benign neurinoma of the appendix. Only 6 cases of neurinoma of the appendix have been reported in Japan, and no guidelines for appropriate therapy have been established.

Key words
neurinoma, appendix

Reprint requests
Hirohiko Satoh Department of Surgery, National Hospital Organization, Kochi National Hospital
1-2-25 Asakura-Nishi-machi, Kochi, 780-8077 JAPAN

Accepted
May 31, 2006

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