A Case of Primary Gastric Natural Killer/T-cell Lymphoma, Nasal type

Akio Yamasaki, Tadaaki Eto, Naoki Maehara, Hideki Hidaka, Shuichiro Uchiyama, Kousuke Marutsuka* and Kazuo Chijiiwa

Department of Surgery 1, and Department of Pathology*, School of Medicine, University of Miyazaki

We report a rare case of primary nasal gastric Natural Killer/T-cell (NK/T-cell) lymphoma. A 46-year-old man having an aberration in gastric fluoroscopy screening. Gastroscopy had two erosive gastric lesions pathologically diagnosed as lymphoma. Immunohistochemical studies showed lymphoma cells to be positive for CD56 and TIA-1 and negative for CD8, CD79α and EBER-1, indicating NK/T-cell lymphoma. Systemic examinations with positron-emission tomography and compouted tomography (CT) showed no other lesions and no association with human T-cell lymphotropic virus type I. Under a definitive diagnosis of primary gastric NK/T-cell lymphoma, nasal type, stage I, he underwent total gastrectomy with D2 lymph node dissection. Since no lymph node metastasis nor invasion to muscularis propria were observed, no additional chemotherapy was added. He remains alive without recurrence 6 months after surgery.

Key words
malignant lymphoma, NK/T-cell, primary gastric

Reprint requests
Kazuo Chijiiwa Department of Surgery 1, School of Medicine, University of Miyazaki
5200 Kihara, Kiyotake, Miyazaki, 889-1692 JAPAN

Accepted
June 28, 2006

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