A Case Report of Non-Recurred Long-Term Survival After Resection for Undifferentiated Rectal Cancer with Systemic Multiple Lymph Node Metastases Successfully Treated by Preoperative Chemotherapy

Koichi Kinoshita, Michiyuki Kanai and Arimichi Takabayashi

Department of Surgery, Kitano Hospital, Tazuke Kofukai Medical Research Institute

A 62-year-old man with undifferentiated rectal cancer and systemic lymph node metastases underwent chemotherapy with 5-FU, l-LV, and CPT-11. Both lymph node metastases and rectal cancer completely disappeared after 5 cycles of treatment. Rectal cancer recurred locally after 9 months of Complete Response and was resected locally. Five months after local resection, we again resected again local rectal cancer by abdominoperineal resection. The man survived for 3.5 years after the initial chemotherapy. This case is rare in having systemic lymph node metastases of rectal cancer controlled by chemotherapy followed by radical surgery.

Key words
neoadjuvant chemotherapy, undifferentiated rectal cancer, systemic lymph node metastasis

Reprint requests
Arimichi Takabayashi Department of Surgery, Kitano Hospital, Tazuke Kofukai Medical Research Institute
2-4-20 Ogimachi, Kita-ku, Osaka, 530-8480 JAPAN

Accepted
September 27, 2006

To read the PDF file you will need Abobe Reader installed on your computer.