A Case of non-B, non-C, Juvenile Hepatocellular Carcinoma

Masaki Kaibori, Morihiko Ishizaki, Yoichiro Uchida, Takamichi Saito, Yoshiko Uemura¹⁾, Toshihito Seki²⁾ and Yasuo Kamiyama

Department of Surgery and Department of Pathology¹⁾, Hirakata Hospital, Kansai Medical University
Third Department of Internal Medicine, Takii Hospital, Kansai Medical University²⁾

A 20-year-old man with non-B non-C hepatitis referred for severe upper abdominal pain underwent. A transarterial chemoembolization for a ruptured liver tumor. Abdominal computed tomography (CT), magnetic resonance imaging (MRI), and angiography showed tumors 7 cm in diameter in segment 7/8, 6 cm in segement 6, and 1 cm in segment 4. Serum AFP was 25,100 ng/ml. An extended right hepatic lobectomy showed stage IVa (T4N0M0). Histological examination of the resected tumor showed moderately differentiated hepatocellular carcinoma (HCC). He is doing well without recurrence 30 months after surgery. Juvenile HCC is relatively rare, and the most common background factor in it in Japan is continuous infection with the hepatitis B virus. This rare case of juvenile HCC had no serum hepatitis virus markers. Such a tumor should be completely resected immediately while liver function is comparatively good, even in advanced juvenile HCC.

Key words
juvenile hepatocellular carcinoma, hepatic resection

Reprint requests
Masaki Kaibori Department of Surgery, Hirakata Hospital, Kansai Medical University
2-3-1 Shinmachi, Hirakata, 573-1191 JAPAN

Accepted
October 25, 2006

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