A Complete Response in Left Metastatic Tonsillar Tumor Treated with TS-1 Based Chemotherapy After Curative Resection of Gastric Carcinoma: A Case Report

Kazuhito Minami, Yasuhiro Tsutani, Takahisa Suzuki, Eiji Miyahara, Akira Kameda and Yoshihiro Noso

Department of Surgery, Saiseikai Hiroshima Hospital

A 58-year-old woman diagnosed with gastric carcinoma underwent total gastrectomy with D2 lymph node dissection in September 2005. The definitive diagnosis was f Stage IIIB gastric carcinoma (pT3, pN2, sH0, sP0, pCY0, cM0) and surgery had curability B based on the Japanese classification of gastric carcinoma, 13^th edition. Histological findings of resected specimens showed poorly differentiated non solid adenocarcinoma (por2). She underwent adjuvant chemotherapy at 100 mg/day of oral TS-1 from November 2005. She reported an abnormal throat sensation 3 days after beginning TS-1 treatment. Her left palatine tonsil had swollen to 30 mm and biopsied samples showed group V (por2). The left tonsillar tumor was diagnosed as metastasis from gastric carcinoma, because the biopsied samples were similar pathologically to the resected gastric specimen. No other metastatic sites were seen in computed tomography. A complete response was acquired in the metastatic tonsillar tumor 14 days after TS-1 treatment and maintained for 8 months in June 2006. TS-1 treatment may thus contribute to good quality of life and improved poor prognosis.

Key words
tonsillar metastasis, gastric carcinoma, oral TS-1 therapy

Reprint requests
Kazuhito Minami Department of Surgery, Saiseikai Hiroshima Hospital
2-3-10 Kita-shinchi, Saka-cho, Aki-Gun, 731-4311 JAPAN

Accepted
April 25, 2007

To read the PDF file you will need Abobe Reader installed on your computer.