A Case of Jejunal Cancer with Lung Metastases and Peritoneal Dissemination Dramatically effected by Postoperative TS-1 Chemotherapy

Naoto Gunji, Takeshi Gohongi, Hiroyuki Iida, Reiko Nakai, Yasuhiro Takase, Takesaburo Ogata* and Kazuo Orii

Department of Surgery and Department of Pathology*, Tsukuba Gakuen Hospital

We present a rare case of advanced jejunal cancer with good response to TS-1 chemotherapy. A65-year-old woman admitted for appetite loss and vomiting, was found in enhanced abdominal CT to have thickening of jejunum wall and a large tumor mass on the right side of the ascending colon. Contrast examination of the small intestine showed local jejunum stenosis and dilation at its oral site. Chest CT showed two metastatic tumor nodules at right S8a 12 mm in diameter and the left S1+2 5 mm in diameter. Partial jejunectomy to reduce her ileus syndrome showed that the 5×3 cm jejunal tumor measuring was mucinous adenocarcinoma with multiple disseminated nodules in the peritoneum. Postoperative chemotherapy with TS-1 for 24 months gradually reduced X-ray shadows of peritoneal and pulmonary metastases and she remains apparently healthy at present.

Key words
carcinoma of small intestine, TS-1, chemotherapy

Reprint requests
Naoto Gunji Department of Surgery, Tsukuba Gakuen Hospital
2573-1 Kamiyokoba, Tsukuba, 305-0854 JAPAN

Accepted
March 28, 2007

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