A Case Report of Gastrointestinal Mesenchymal Tumor which is Detected by Perforation Peritonitis

Tatsuya Shonaka, Kazuhito Misawa, Kazutomo Kikuchi, Keisa Takeda, Yumi Okawa, Yayoi Ogawa* and Hidekazu Sano

Department of Surgery and Department of Pathology*, Sapporo City General Hospital

We report a case of a fairly rare mesenchymal gastrointestinal mesenchymal tumor (GIMT) of the colon. A 46 year-old man with a history of sudden epigastric pain was found in Computed Tomography (CT) to have 6-cm diameter mass in the transverse colon complicated by peritoneal free air and massive fluid accumulation. Emergency surgery showed the mass to be a perforated submucosal tumor leading to peritonitis. Histologically, the resected tumor showed increased spindle cells with neutrophilic proliferation at the perforation. Immunofluorescence microscopy showed positive findings for vimentin but negative for c-kit, CD34, S-100, and SMA all compatible with GIMT.

Key words
colon, gastrointestinal stromal tumor (GIST), perforation peritonitis

Reprint requests
Tatsuya Shonaka Department of Surgery, Sapporo City Hospital
North11-13, Chuo-ku, Sapporo, 060-8604 JAPAN

Accepted
May 30, 2007

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