A Case of Crohn's Disease with Huge Perineal Defect that Infliximab was Effective

Katsuhisa Ohashi, Satomi Furukawa, Kenichi Komura, Tetsuro Yamana, Kinya Okamoto, Tomoko Takahashi, Kunihiko Obara, Daisuke Okada and Rikisaburo Sahara

Department of Proctology, Social Health Insurance Hospital

A 25-year-old man diagnosed with uncontrollable perianal abcess was admitted. At first, we strongly suspected of heaving Crohn's disease, which was eventually. Later, we confirmed Crohn's disease pahologically from perinial tissue. The perineum was inveterate, and developed into a huge defect. After medication by infliximab, intractable pain under morphine and the defect immediately improved. No case has been reported, to our knowledge, that infliximab being effective for a huge perineal defect and uncontrollable pain in Japan.

Key words
Crohn's disease, infliximab, anal fistula

Reprint requests
Katsuhisa Ohashi Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University, Graduate of Medicine and Dentistry
2-5-1 Shikata-cho, Okayama, 700-8558 JAPAN

Accepted
May 30, 2007

To read the PDF file you will need Abobe Reader installed on your computer.